Used as 1,3-bifunctional reagent in the pyrimidine to pyridine ring transformations.1 Has been applied for heterocyclization with the introduction of alkoxycarbonylmethyl group,2 acylation by diacid chlorides,3 palladium-catalyzed arylation,4 selective monoalkylation of diethyl malonate, ethyl cyanoacetate, and malononitrile,5 reaction with benzal-4-acetylanilines,6 reaction with Iodolevoglucosenone under Michael reaction conditions 7 and reaction with aryl bromides catalyzed by palladium complexes with chelated phosphine ligands.8
1. Tetrahedron Lett. 1992, 33, 3695.
2. Chem. Heterocycl. Compd. 1994, 30, 126.
3. Russ. Chem. Bull. 1987, 36, 2419.
4. J. Am. Chem. Soc., 2001, 123, 4641.
5. J. Org. Chem., 1997, 62, 5235.
6. Indian J. Chem., Sect B 2008, 47B, 778.
7. Russ. J. Org. Chem. 2001, 37, 1088.
8. J. Mol. Catal. A: Chem. 2002, 186, 53.