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024890

024890-1g



TNTU


CAS Number: 125700-73-4
   
Molecular Formula: C14H20BF4N3O3
   
Molecular Weight: 365.14
   
MDL Number: MFCD07369131


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024890-1g
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024890-5g
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024890-25g
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Purity:98%
Mp:216-219°
 
Pictograms:
Signal Word:Warning
Hazard Statements:H302, H315, H319, H335
Precautionary Statements:P260, P264, P270, P271, P280
SDS: See MSDS
 

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A coupling reagent for peptide and organic synthesis.1,2 Applied in synthesis of  leuenkephalin amide on a solid support suspended in aq. 50% EtOH,2 synthesis of (2S,3aS,7aS)-1-[(S)-alanyl]octahydro-1H-indole-2-carboxylic acid derivatives,3 active ester formation and oxazolone formation by  reaction with Z-Gly-Ala-OH,4  and formation of Fmoc-L-Ala-L-Phlac-OCH2Ph  and Fmoc-D-Ala-L-Phlac-OCH2Ph.5 Also used for fabricating a novel reusable electrochemical immunosensor by immobilizing of 3-aminophenylboronic acid conjugated thiol-mixed monolayer on gold though TNTU as linkage.6

Reference

1.        Pept., Proc. Eur. Pept. Symp., 20th1989, 37
2.        Protein Peptide Lett. 200613, 189.
3.        EP 1420030 A2 200405192004.
4.        Pept., Proc. Eur. Pept. Symp., 24th1996, 455.
5.        J. Chem. Soc., Perkin Trans. 21995, 2335.
6.        Talanta 200877, 815.

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