A reagent for proteomics research. Applied in design of novel aminopyrrolidine factor Xa inhibitors from a screening hit,1 preparation of N-(1-arylpyrazol-4-yl) sulfonamides as parasiticides,2 and research on kinesin spindle protein (KSP) inhibitors.3 Also used as a reagent in reactions with heptafluoro-5,6-dihydro-2H-1,4-oxazine and heptafluoro-3,4-dihydro-2H-pyrrole,4 and preparation of heptafluoropropyl fluoroalkyl ethers as chlorofluorohydrocarbon alternative.5
Reference
1. Eur. J. Med. Chem. 2009, 44, 2787.
2. WO 2005090313 A1 20050929, 2005.
3. J. Med. Chem. 2008, 51, 4239.
4. J. Fluorine Chem. 2001, 110, 63.
5. JP 08034755 A 19960206, 1996.