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038199

038199-5g



1,1'-Carbonyl-di-(1,2,4-triazole)


CAS Number: 41864-22-6
   
Molecular Formula: C5H4N6O
   
Molecular Weight: 164.13
   
MDL Number: MFCD00043399


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038199-5g
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038199-25g
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038199-100g
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Purity:95%
Mp:145-150°
 
Pictograms:
Signal Word:Danger
Hazard Statements:H302, H318, H361, H402
Precautionary Statements:P280, P301 + P330 + P331, P302 + P352, P304 + P340, P305 + P351 + P338
SDS: See MSDS
 

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Abbrieviated as CDT. Reagent for preparing the reactive acyl triazolides from carboxylic acids,1  synthesis of novel imidazoles and triazoles from alcohols and phenols,2 conversion of alcohols to alkylheterocycles,3 microwave-assisted synthesis of 5-functionalized 1,2,4-triazolium ylides starting from N',N'-disubstituted carbohydrazonamides,4 and synthesis of a novel carbamate-glucuronide.5 Reactions with di-Et phosphono-α-aminoalkylcarbonitriles or ortho-hydroxy-arenonitriles to give 4-methoxy(aralkoxy)imino-benzo[1,3]oxazin-2-ones or 3-alkoxy-4-imino-imidazolidin-2-ones respectively.6,7  Conjugation reagents for preparing immunogens.8 Reaction of unprotected glucose with acyl triazolide to the β-D-glucosyl ester.9 Dehydrating agent which reacts with H2O2 giving singlet oxygen, used e.g. for epoxidations.10

References:

1.        Angew. Chem. 196274, 407.
2.        Synthesis 2000, 2019.
3.        J. Org. Chem. 199762, 7319.
4.        Eur. J. Org. Chem. 200835, 6029.
5.        Carbohydr. Res. 1989190, C11.
6.        Tetrahedron 200460, 2409.
7.        Synthesis 2004, 1987.
8.        WO 2011041003 A2 201104072011
9.        Helv. Chim. Acta 198063, 277.
10.        J. Org. Chem. 197944, 1485.


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