A chelating agent with a much higher affinity for calcium than for magnesium ions. Mainly used for making buffer solutions that resemble the environment inside living cells,1 treatment of animals with cerium poisoning,2 the separation of thorium from the mineral monazite,3 and as a compound in elution buffer in the protein purification technique known as Tandem Affinity Purification (TAP).4 Often employed in dentistry and endodontics for the removal of smear layer.5
1. J. Neurosci. 2004, 24, 9752.
2. Indian J. Exp. Biol. 2004, 42, 876.
3. Fresenius J. Anal. Chem. 1987, 326, 469.
4. PNAS 2009, 106, 8998.
5. J. Clin. Pediatr. Dent. 2003, 28, 69.