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008580

008580-1g



2,2,2-Trifluoroethyl methanesulfonate

CAS Number: 25236-64-0
   
Molecular Formula: C3H5F3O3S
   
Molecular Weight: 178.13
   
MDL Number: MFCD00025058


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008580-1g
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008580-5g
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008580-25g
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008580-100g
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Purity:99%
Density:1.513
Refractive Index:1.367
 
Pictograms:
Signal Word:Warning
Hazard Statements:H314, H318
Precautionary Statements:P280, P301 + P330 + P331, P302 + P352, P304 + P340, P305 + P351 + P338, P310
UN#:UN3265
Packing Group:III
Hazard Class:8
Flash Point:104°
SDS: See MSDS
 
Limited Quantities:5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities:Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

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A reagent to introduce CF3CH2 moiety into a molecule by nucleophilic substitution for the pharmaceutical, agrochemical, and performances markets.1 Used for synthesis of trifluoroethyl benzyl sulfide,2 fluorinated aryl and vinyl ethers,3 and imidazole derivatives for the manufacture of pharmaceutical compositions for the treatment and prevention of mGluR5 receptor mediated disorders.4

1. Org. Process Res. Dev., 2006, 10, 194.
2. Can. J. Chem. 1987, 65, 2385.
3. Eur. J. Org. Chem. 2009, 3513.
4. U.S. Patent 7091222. 

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