A chemically and thermally stable perfluoro macrocycle that coordinates anions rather than cations and is extremely biocompatible.1 Commonly used in NMR imaging applications as a F- MRI/MRS agent or as a oxygen sensor due to its high signal-to-noise ratio and 20 equivalent 19F nuclei that give rise to a single resonance (-92.5 ppm) in NMR imaging.2,3,4,5
1. Inorganic Fluorine Chemistry 1994, 216.
2. Magn. Reson. Med. 2005, 32, 88.
3. Anal. Biochem. 2009, 387, 315.
4. Magn. Reson. Mater. Phys., Biol. Med. 2004, 17, 288.
5. Circulation 2008, 118, 140.