Mainly used as a chiral ligand for synthesis of effective chiral catalysts such as bistriflamide catalyst for the enantioselective Diels-Alder reaction1 and Ruthenium complex catalysts for asymmetric hydrogenation reactions.2 Also used to elucidate the chirality of the commercially available analgesic, ibuprofen by the formation of amide and ammonium salt derivatives.3
1. Org. Synth. 1993, 71, 30.
2. Polyhedron 2007, 26, 329.
3. J. Chem. Educ. 1996, 73, 569.