Building block in organic syntheses. Mainly used in the interaction with C-nucleophiles such as organo-magnesium and -zinc compounds, and phosphorous nucleophiles such as diethyl phosphite, triethyl phosphite, tributyl phosphine and tris(diethylamino) phosphine.1,2,3 A protecting reagent in peptide synthesis. The reaction with amino acids proceeds readily at room temperature to give protected amino acids without racemization. 4,5 A useful intermediates for preparing pesticides.6
1. J. Fluorine Chem. 1993, 65, 25.
2. J. Fluorine Chem. 1998, 90, 1.
3. J. Fluorine Chem. 2005, 126, 931.
4. Synthesis 1991, 207.
5. Molecules 1997, 2, 186.
6. U.S. Patent Publication 2005/0288511