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013519
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4,5-Dicyanoimidazole
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| Product Number | Your Price | Order |
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013519-25g |
$49.00 |
In stock
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013519-100g |
$150.00 |
In stock
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Peptide and oligonucleotides reagents. Commonly used in activation of nucleoside phosphoramidites during solid-phase oligonucleotide synthesis 1, synthesis of nucleoside phosphoramidites 2, synthesis of novel nucleosides 3,4, synthesis of 1-alkyl dicyanoimidazole derivatives and as a precursor to 2-bromo-4,5-dicyanoimidazole 5. It is an alternative to the tetrazole-based activators and is less acidic but is a much more nucleophilic activator. 1. Nucleic Acid Res. 1998, 26, 1046. 2. Tetrahedron Lett. 1996, 37, 973. 3. J. Am. Chem. Soc. 2009, 131, 8496 4. Nucleosides & Nucleotides 1994, 13, 2307 5. Encyclopedia of Reagents for Organic Synthesis, 2001 |
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