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Visit Us:Marm 2024 Celebrating Discovery

June 5th-June 8th, 2024

The Pennsylvania State University

University Park, PA

 

Feel free to ask about special packaging, quantities not listed, or if you can't find a specific item listed on our page.Please contact us








106409

106409-1L



Capping A, 20% NMI in ACN, for AKTA oligopilot™ (Acetonitrile / N-methylimidazole, v/v = 80:20) 1L, 2.5L, GL45 thread emp Biotech GmbH


CAS Number:
   
Molecular Formula:
   
Molecular Weight: 0.00
   
MDL Number:


 Item #PriceQuantityAdd to Cart 
106409-1L
Regular Price: $99.00
Your Discounted Price: $0.00
In Stock USA
106409-2.5L
Regular Price: $165.00
Your Discounted Price: $0.00
In Stock USA



 
Pictograms:
Signal Word:Danger
Hazard Statements:H225, H302, H312, H314, H332
Precautionary Statements:P201, P261, P280, P301 + P310, P301 + P330 + P331, P302 + P350, P304 + P340, P305 + P351 + P338, P310
UN#:UN2924
Packing Group:II
Hazard Class:3
, 8

SDS: See MSDS
 
Limited Quantities:1.0 L (0.3 gallon) (liquid)
Excepted Quantities:Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)

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For each synthesis cycle, up to 1 to 2 % of free 5'-hydroxy groups remain after the phosphoramidite coupling step has been completed. By running a subsequent "Capping" step using an anhydride, these free hydroxyl groups are converted to acetates and are hindered from further chain elongation and formation of long oligonucleotides with incorrect sequences. For optimal acetylation, a solution of acetic anhydride in Tetrahydrofuran or acetonitrile (Capping A) will be mixed in situ during reaction with a catalytic acting solution of N-methylimidazole (Capping B). Additives such as pyridine and lutidine function as mild bases to enhance the efficiency of the capping reaction.

Product of emp Biotech GmbH
Size bottle:
1L with GL45 thread, emp Biotech part no. NC-0705-N001.0-001
2.5L with GL45 thread, emp Biotech part no. NC-0705-N002.5-001

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